Monoidal uniqueness of stable homotopy theory Brooke Shipley Abstract. We show that the monoidal product on the stable homotopy category of spectra is essentially unique. This strengthens work of this author with Schwede on the uniqueness of models of the stable homotopy theory of spectra. Also, the equivalences constructed here give a unified construction of the known equivalences of the various symmetric monoidal categories of spectra (S-modules, W-spaces, orthogonal spectra, simplicial functors) with symmetric spectra. As an application we show that with an added assumption about underlying model structures Margolis' axioms uniquely determine the stable homotopy category of spectra up to monoidal equivalence.