\title{Blocks inequivalent to their Frobenius twists} \author{David Benson, Radha Kessar} \address {Department of Mathematics, University of Aberdeen, King's College, Aberdeen AB24 3UE, Scotland } \begin{abstract} Let $k$ be an algebraically closed field of characteristic $p$. We give a general method for producing examples of blocks $B$ of finite group algebras that are not Morita equivalent as $k$-algebras to the Frobenius twist $B^{(p)}$. Our method produces non-nilpotent blocks having one simple module and elementary abelian defect group. These also provide the first known examples of blocks where there is a perfect isotypy at the level of ordinary characters with all the signs positive, but no derived equivalence between the blocks. We do not know of any examples of blocks $B$ that are not Morita equivalent to the second Frobenius twist $B^{(p^2)}$. \end{abstract}