Orbital Differential Diagnosis by Location

index

 

Common

Uncommon

Rarities

Intraconal-
Optic Nerve
  1. Optic neuritis
  2. Papilledema
  3. Orbital apex #
  4. Perineuritis 2ry to pseudotumour
  5. Optic Gliom
  1. Optic nerve sheath meningioma
  2. Sarcoidosis
  3. Metastases
  1. Haemagioblastoma
  2. Lymphoma
Intraconal-
Other
  1. Cavernous haemangioma
  2. Inflammatory pseudotumour
  3. Varix
  1. Neurfibroma
  2. Lymphangioma
  3. Dilated ophthalmic artery due to AVM
  4. Metastasis
  5. Lymphoma (usually extraconal)
  6. Capillary haemagioman (usually extraconal)
  1. Schwannoma
  2. Haemagiopericytoma
  3. Yolk sac tumor
  4. Mesenchymal chondrosarcoma
  5. Granular cell myoblastoma
Extraconal
  1. Dermoid
  2. Lymphoma
  3. Capillary haemangioma
  4. Rhabdomyosarcoma
  1. Neurofibromas
  2. Metastases
  1. Fibrous histiocytoma
Preseptal
  1. Xanthelasma & others
  2. Basalioma
  1. Capiallary haemangioma
  2. Dermoid
  3. Lymphoma
  4. Fibroma
  5. Neruofibroma
  1. Metastases
  2. Melanosarcoma
Periosteal space
  1. Mucocele
  2. Orbtial #
  3. Subperiosteal abscess
  4. Tumour of paranasl sinsuses
  5. Osteoma
  6. Metastases
  7. Dermoid, epidermoid
  8. Meningioma
  9. Rhabdomyosarcoma
  1. Fibrous dysplasia
  2. Craniofacial dysplasia
  3. Wegener' granulomatosis
  4. Plasmocytoma
  5. Cholesterol cyst
  6. Paget's disease
  1. Sphenoid wing malformation
  2. Histiocytosis
  3. Encephalocele
  4. Osseous tumours
    1. giant cell tumour
    2. brown tumour
    3. aneurysmal bone cyst
  5. Osteopetrosis
  6. Osteosarcoma of children with retinoblastoma
Lacrimal gand
  1. Dacryoadenitis
  2. Inflammatory psseudotumour
  3. Abscess
  1. Lymphoma
  2. Dermoid
  3. Sarcoidosis
  4. Pleomorphic adenoma
  5. Adenoid cystic carcinoma
  6. Sjogren's syndrome
  1. Wegner's granulomatosis
  2. Mikulicz' syndrome
  3. Metastases
Lacrimal duct
  1. Papilloma
  2. Transitional cell carcinoma
  3. Epidermoid carcinoma
  4. Melanoma
   
Orbital apex and cavernous sinus
  1. Pituitary adenoma
  2. Meniongioma
  3. Empty sella
  4. Arachnoid cyst
  5. Craiopharyngioma
  6. Optic chiasm glioma
  1. Metastases
  2. Tolosa-hunt syndrome
 
Extraocular Muscles
  1. Thryoid orbitopathy
  2. Myositis
  3. Inflammatory pseudotumor
  1. Metastases
  2. Wegner's granulomatosis
  3. Acromegaly
  4. Granular cell myoblastoma
  5. Lithium therapy